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Autism

Advancements made in regenerative medicine are swiftly approaching the development of an autism stem cell therapy. This is because stem cell therapy has already been established as an effective approach to many neurological conditions, as well as immunological, musculoskeletal, and physiological disorders and diseases.

Stem cells have a unique ability to influence metabolism and the immune system as well as to restore damaged cells and tissues. These therapies positively affect all body organs and systems, including the most important organ of all — the brain.

Now stem cells are showing great promise for children and adults who need help in combating the symptoms of autism. While this therapy can be very beneficial, it is not a cure for autism in any way. The goal of stem cell therapy is to improve patients’ behavior and overall well-being.

The rationale behind treating autism with umbilical cord tissue-derived mesenchymal stem cells is that autism, and its degree of severity, has been significantly correlated inflammatory and neuro-inflammatory cytokines including macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC). Intravenous administration of umbilical cord MSCs has been shown in multiple clinical trials to decrease inflammation.

Decreasing inflammation in the autistic patient may alleviate symptoms of autism.

The treatment of immune deregulation using stem cells in autism, has been shown to not only cause an improvement of intestinal and systemic symptomatology, but also to profoundly influence neurological function. Numerous reports exist of temporary neurological improvement by decreasing intestinal inflammation through either antibiotic administration or dietary changes. 

Now stem cells are showing great promise for children and adults who need help in combating the symptoms of autism. While this therapy can be very beneficial, it is not a cure for autism in any way. The goal of stem cell therapy is to improve patients’ behavior and overall well-being.

The rationale behind treating autism with umbilical cord tissue-derived mesenchymal stem cells is that autism, and its degree of severity, has been significantly correlated inflammatory and neuro-inflammatory cytokines including macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC). Intravenous administration of umbilical cord MSCs has been shown in multiple clinical trials to decrease inflammation.

Decreasing inflammation in the autistic patient may alleviate symptoms of autism.

The treatment of immune deregulation using stem cells in autism, has been shown to not only cause an improvement of intestinal and systemic symptomatology, but also to profoundly influence neurological function. Numerous reports exist of temporary neurological improvement by decreasing intestinal inflammation through either antibiotic administration or dietary changes. 

Although some anti-inflammatory treatments have yielded beneficial effects, no clinical agent has been developed that can profoundly suppress inflammation at the level of the fundamental immune abnormality. We believe mesenchymal stem cell administration may be used for this purpose.

The medications used for treatment often lack evidence of safety and efficacy for the core features of Autism, and instead target maladaptive behaviours and comorbid psychopathology (i.e. irritability, depression, anxiety, hyperactivity and obsessive-compulsive behaviours).

Concerns over safety have limited the availability of approved psychotropic medications for children in general, and have been encouraging the development of biomedical treatments to target specific biological issues or symptoms. These include the use of: melatonin, acetylcholinesterase inhibitors,naltrexone, carnitine, tetrahydrobiopterin, vitamin C, glutamate antagonists, special dietary supplements, hyperbaric oxygen treatment, immunomodulation and anti-inflammatory treatments, oxytocin, acupuncture, music therapy and vision therapy.

Although some anti-inflammatory treatments have yielded beneficial effects, no clinical agent has been developed that can profoundly suppress inflammation at the level of the fundamental immune abnormality. We believe mesenchymal stem cell administration may be used for this purpose.

The medications used for treatment often lack evidence of safety and efficacy for the core features of Autism, and instead target maladaptive behaviours and comorbid psychopathology (i.e. irritability, depression, anxiety, hyperactivity and obsessive-compulsive behaviours).

Concerns over safety have limited the availability of approved psychotropic medications for children in general, and have been encouraging the development of biomedical treatments to target specific biological issues or symptoms. These include the use of: melatonin, acetylcholinesterase inhibitors,naltrexone, carnitine, tetrahydrobiopterin, vitamin C, glutamate antagonists, special dietary supplements, hyperbaric oxygen treatment, immunomodulation and anti-inflammatory treatments, oxytocin, acupuncture, music therapy and vision therapy.

In the midst of these various therapies, stem cell therapies are emerging as the future of molecular and regenerative medicine and they are providing new opportunities for ASD interventions.

An important characteristic of mesenchymal stem cells is their ability to constitutively secrete immune inhibitory factors, this is believed to further allow inhibition of immunity in an antigen specific manner, as well as to allow the use of such cells in an allogeneic fashion without fear of immune-mediated rejection. Antigen immune suppression is believed to allow these cells to shut off autoimmune processes.

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Contact Us to discuss your treatment at Cellular Hope Institute

Cellular Hope Institute – Datran Center 9100 S Dadeland Boulevard, Suite 1500. Miami Fl. 33156 United States

305 560 5337

info@cellularhopeinstitute.com

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Contact Us to discuss your treatment at Cellular Hope Institute

Cellular Hope Institute – Datran Center 9100 S Dadeland Boulevard, Suite 1500. Miami Fl. 33156 United States

305 560 5337

info@cellularhopeinstitute.com

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