Over the course of modern history, chemotherapy and cytotoxic pharmaceuticals have dominated most cancer treatments. Despite the fact that these traditional methods of treating cancer are successful in killing cancer cells, they also destroy many of the body’s healthy cells and neurotransmitters, causing serious side effects. A functional medical approach has always been a single goal of scientists in the fight against cancer: to kill only cancer cells and reverse systemic autoimmune disease.
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Natural Killer Cells
Natural killer cells or NK are the body’s first line of defense viruses and cancerous cells in the body, and are innately capable of finding and destroying transformed cells. Recent advances in gene therapies, mRNA technology, regenerative medicine, and non-toxic radiology have helped us get much further than ever before. Currently, our therapeutic goals are primarily to strengthen your body’s ability to fight disease and cancer by strengthening its own natural defense mechanisms.
Due to its repair and regeneration capacity, NK cells, or natural killer cells are always being used by the human immune system to prevent cancer. Cancerous cells, precancerous cells, and viruses can and do be destroyed by our immune system while recognizing healthy cells and not harming them. With this new targeted therapy (autologous NK cellular immunotherapy), the patient’s immune system fights and destroys cells and organisms that are harmful to the body.
NK cells are a type of white blood cell known as a lymphocyte. Humans are born with these lymphocytes as part of their congenital immune system. Activated lymphocyte therapy works by directly attacking and killing cancer cells by infusing autologous Enriched NK cells from the patient’s immune system.
Killer cells are responsible for our bodies’ ability to reject “foreign mutant cells” such as tumors and virally infected cells. There are two types of natural killer cells: cytotoxic T cells and natural killer T cells. These tiny granules within its cytoplasm contain very specific proteins (proteases & perforins) called granzymes. Natural T Killer cells produce a wide variety of cytokines, such as:
- Interleukin (IL-10)
- Tumor necrosis factor α TNFα
We help you Enhance your own body’s ability to fight, repair and restore through Advanced Regenerative Medicine therapies.
Natural Killer Cells: The Power Of Nature
As one of the most promising breakthroughs in cancer treatment, cell therapy uses immune cells to attack tumors. Currently, first-generation approaches focus on T-cell therapy, which has shown promising results in hematologic malignancies, but that has been plagued with unwanted side effects, and has yet to show similar results in solid tumors.
The potential benefits of NK cell therapy include:
- It targets multiple pathogenic antigens with a measurably higher degree of cytotoxicity.
- Maintain a better level of control to reduce the risk of cytokine storms.
- Are not dependent on patient-specific immune cells, and are produced from a variety of sources.
NK cell therapy platform maximizes the therapeutic effect of allogeneic NK cells by increasing their expansion, enhancing their targeting, and extending their survival to unleash powerful and sustained anti-cancer immune responses.
Our CAR-NKs are engineered to address the limitations of current CAR-T therapies, including safety concerns and tumor targeting.
Engineered Car-Nk Cells
NK cells are the cornerstones of innate immunity
- Cell source derived from allogeneic donors, which is scalable for off-the-shelf use.
- The use of proprietary technologies such as expansion, persistence, cryopreservation, and tumor targeting.
Targeting receptor, OX40 costimulatory domain, CD3ζ signaling moiety, membrane bound IL-15