Multiple Sclerosis

This condition is caused by an immune mediated attack targeting components of the myelin sheath. The myelin sheath is the sleeve of fatty tissue that protects nerves and neurons and helps them carry messages back and forth between the brain and the rest of the body, is also known to act as an “insulator” for neurons so that they can communicate properly with each other. 

Mesenchymal stem cells (MSCs), have immune regulatory properties which may stop the immune system from attacking the myelin sheath.Current approaches, such as interferon, copaxone, or immuno-suppressants all act in a nonspecific manner blocking immune responses against the myelin sheath. While these approaches are useful for reducing the severity of disease, they do not repair the damage to nervous system tissue that has already.

The management of multiple sclerosis involves the treatment of the acute relapse, prevention of future relapse, treatment of complications, and management of the patient’s disability.  Our Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as non-pharmacologic treatments, such as physical and occupational therapy.

Stem Cells not only regulate the immune system from attacking the myelin sheath, but also have the potential to repair nerve tissue. Adult stem cells possess the ability to repair damaged cells leading to tissue regeneration and ultimately promoting the healing process. 
The objective of our therapeutic approach is to provide the patient with a treatment that stimulates his / her immune system, promotes cellular regeneration and improves symptoms associated with Multiple Sclerosis. The administration of Adult Stem Cell should serve to compliment the patient’s current treatment regimen or to promote healing when current treatment is not responding.

Mesenchymal stem cells (MSCs), have immune regulatory properties which may stop the immune system from attacking the myelin sheath.Current approaches, such as interferon, copaxone, or immuno-suppressants all act in a nonspecific manner blocking immune responses against the myelin sheath. While these approaches are useful for reducing the severity of disease, they do not repair the damage to nervous system tissue that has already.

The management of multiple sclerosis involves the treatment of the acute relapse, prevention of future relapse, treatment of complications, and management of the patient’s disability.  Our Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as non-pharmacologic treatments, such as physical and occupational therapy.

Stem Cells not only regulate the immune system from attacking the myelin sheath, but also have the potential to repair nerve tissue. Adult stem cells possess the ability to repair damaged cells leading to tissue regeneration and ultimately promoting the healing process. 
The objective of our therapeutic approach is to provide the patient with a treatment that stimulates his / her immune system, promotes cellular regeneration and improves symptoms associated with Multiple Sclerosis. The administration of Adult Stem Cell should serve to compliment the patient’s current treatment regimen or to promote healing when current treatment is not responding.

Experience our Individually-Center approach for deep regeneration and wellbeing through our leading-edge cellular therapies

Our Clinical Approach to Multiple Sclerosis
How is Multiple Sclerosis stem cell therapy done?
When can I expect to feel the relief of symptoms?
What symptoms of multiple sclerosis does stem cell therapy relieve?
Why should I choose MS stem cell therapy over more traditional methods?
Can stem cells help treat multiple sclerosis?
Can Stem Cells Cure My Medical Condition?
What are the different cellular therapies available for me?
Which Are The Different Administration Methods That We Use At Our Centers?
Why undertake a treatment with highly-manipulated cells outside of the United States?
What To Expect When getting to our Center Treatment Center
What’s Included as Part of our Treatment?
Understanding what causes your medical condition
Our Clinical Approach to Multiple Sclerosis

Cellular Hope Institute MS stem cell therapy is to target myelin sheath damage in MS patients. The stem cell therapy for MS stimulates regrowth of myelin tissue and improves the health of existing nerve cells. The MS stem cell treatment also helps regrow new, healthy nerve cells to replace the damaged ones.This process is called re-myelination.

But our MS stem cell therapy also addresses the autoimmune side of multiple sclerosis. The stem cell treatment for MS procedure stimulates the patient’s own neural stem cells and other stem cells to repair the immune system and, thus, keep it from attacking itself. This process is referred to as immuno-modulation. 

Both aspects of our MS stem cell therapy are proving to be quite effective in improving quality of life for all of our patients dealing with multiple sclerosis.

How is Multiple Sclerosis stem cell therapy done?

The type of stem cells to use for your stem cell treatments for MS is something that you and your Cellular Hope Institute specialist must speak about during a consultation. Many factors are involved regarding the best option, and these include getting a complete medical examination prior to planning your MS treatment. But in most patients the process of stem cell treatment for MS begins with harvesting the patient’s stem cells. This is a relatively quick and very minimally invasive procedure that draws stem cell-rich tissue from one of two areas of the body where stem cells are stored. The harvesting of stem cells for MS stem cell treatment is virtually painless, needing only a local anesthetic at the area of extraction.

When can I expect to feel the relief of symptoms?

Every patient is different, but most begin to feel a measurable difference in their MS symptoms within a few weeks. This is because it takes time for the stem cells to seek out the damage and reach a sufficient population to effect tissue regeneration and repair to help treat MS.

Improvement to MS symptoms usually builds from there over the course of the next several months.

What symptoms of multiple sclerosis does stem cell therapy relieve?

Most patients using stem cells for multiple sclerosis therapy can expect a variety of symptom relief, which may include the following:

  • Improved Balance and Coordination
  • Reduced or Eliminated Numbness and Tingling
  • An Increase in Energy & Endurance
  • Improvement in Mental Focus and Concentration
  • Reduced or Eliminated Muscle Spasming
  • An Increase in Mobility and Range of Motion
  • An Improvement in Bladder Function
  • Reduced or Eliminated Pain, both Chronic and Acute
  • An Increase in Muscle Strength
  • Memory Improvement
  • Improved Speech
  • Reduced or Eliminated Depression
  • An Improvement in Vision
  • An Increase in Sexual Functions
  • Reduced or Eliminated Headaches
  • An Improvement in the Sense of Touch
  • A Possible Reduction in Medication Needs
Why should I choose MS stem cell therapy over more traditional methods?

Prior to the development of the stem cell procedure coming to the forefront of new therapies for MS, the only recourse for the relief of symptoms was drug-related. Drug therapy may work for a while, but the body builds a tolerance that usually demands ever-increasing doses over time.

In many cases, there can be unpleasant or even life-endangering side effects. For some multiple sclerosis sufferers, drugs don’t work well at all or can even stop working. Often, these are the patients who end up coming to our Center for MS stem cell therapy.

Can stem cells help treat multiple sclerosis?

At present there are no FDA-approved treatments that specifically target the abnormal immune responses in MS. Current approaches, such as interferon, copaxone, or immune suppressants all act in a nonspecific manner blocking immune responses against the myelin sheath. While these approaches are useful for reducing the severity of disease, they do not repair the damage to nervous system tissue that has already occurred and therefore they cannot cure multiple sclerosis.

Mesenchymal stem cells (MSCs), have immune regulatory properties which may stop the immune system from attacking the myelin sheath.

Mesenchymal stem cells may also potentially help remyelination (re-generation of the myelin sheath) of the affected neurons.

Can Stem Cells Cure My Medical Condition?

When we treat a medical condition, we are just treating the condition, not curing it. Neither fresh cells nor cultured cells can cure every disease, but they can do great things as far as reducing the severity of symptoms and stopping the advancement of the condition. Normally, in a lot of chronic degenerative conditions or neurological conditions, several treatments will be needed because the effect of cellular therapies has a time limit. Our unique approach includes a multi-dose treatment plan, in which we apply the cells once, with follow-ups at three, six, and nine month mark. If symptoms begin to occur, another round of treatment is needed.

What are the different cellular therapies available for me?

Our comprehensive stem cell treatment protocols employ well-targeted combinations of Exosomes, allogeneic human Mesenchymal cells, and autologous bone marrow and Adipose derived stem cells to treat the  diseases and conditions listed previously. Our treatment plans are mostly focused on a systemic or whole-body approach to ensure these patients receive the highest quality and quantity of cellular products during their time in our hospital.

Of the different kinds of cellular products available for use, there are two main sources that can be used to target the conditions that have been previously discussed.

Autologous procedures are those in which the patient is their own donor for the cellular therapy treatment. In these kinds of procedures, a doctor takes a sample (usually of bone marrow or adipose tissue) and harvests the cells from it, before administering it locally to the diseased or damaged area. 

Allogeneic procedures are those in which the patient receives cells that have been sourced from a donor that is not the patient. These samples are neonatal tissue and are comprised of umbilical cord blood. They are extensively screened to ensure the quality and health of the cells. 

The type of treatment used depends on a variety of factors, including medical history and age, but at the Cellular Hope Institute, we endeavor to give each patient a personalized, case-by-case treatment plan to ensure that the only possible outcome is a positive one.

Which Are The Different Administration Methods That We Use At Our Centers?

After you’ve been selected a candidate, you will meet with our highly-trained team of medical professionals to devise a treatment plan tailored specifically to have the best results possible given your current condition. Below we will outline the different methods of administering cellular therapies that we use in our medical facilities:

intrathecal-intraarterial
This form of implantation is ideal for neurological conditions because the stem cells are injected past the blood-brain barrier and directly into the spinal fluid, which enables them to reach the spinal cord and brain.

During the procedure, an experienced anesthesiologist inject stem cells into the spinal canal through the lower vertebrae under local anesthesia. They are all performed in a positive airflow room under sterile conditions, and the procedure usually takes about thirty minutes.

Intravenous IV
The safest and simplest method for delivering the stem cells throughout the body. Anesthesia is not required. We may use Lidocaine topical spray to needle prick area beforehand. IV administration usually takes about 20 – 30 minutes.

Intramuscular IM
The stem cells are injected directly into the muscle. Intramuscular implantation is very safe and does not require anesthesia.

Why undertake a treatment with highly-manipulated cells outside of the United States?

A treatment of minimally manipulated, or autologous, stem cells is one in which the patient’s own cells are used to treat their illness without being grown in a laboratory setting. These treatments, while minimally invasive, can only reach a third of the total cell count that could be obtained under more complex laboratory processes, leaving them useful for certain conditions, but not potent enough for more advanced degenerative or neurodegenerative conditions. 

Highly-manipulated cellular therapies are those that use a laboratory to culture and expand cells through the cell’s population. Through this process, samples of cells are grown to contain larger quantities of Mesenchymal Stem Cells, which leads to better patient results. In the case of complex conditions, including chronic degenerative conditions or neurodegenerative conditions, the best results are obtained through an infusion of a larger amount of cells directly to the diseased area. This is an invasive procedure, and because of that it requires a large, highly-specialized medical team to carry it out. That is the reason why many patients are opting to find the best results in the best facilities available, which are overseas, since current regulations prevent practices in the States from treating their patients in this manner.

What To Expect When getting to our Center Treatment Center

The Cellular Hope Institute’s offices are located in the Amerimed Hospital in Cancun, which is accredited both by the Mexican General Health Council and the Canadian Accreditation Council. There, we have a highly-qualified team in many specialties, including pediatricians, radiologists, neurologists, anesthesiologists and regenerative medicine specialists, who convene with each other to produce the most reliable, efficable patient experience available.

Aside from it’s proximity to the United States and pleasant climate and sights, Our facilities in Cancun are top-notch, and include a laboratory to culture-expand cells, a process that yields better patient results, and a cryopreservation unit to keep these extracted samples stored safely until they are needed.

What’s Included as Part of our Treatment?

Before the first day of treatment, we go over the patient’s medical history, including previous and current treatments including physical therapy and cognitive therapy. We interview the patients to know more about them in order to form a custom treatment plan. On your first day in Cancun, we have scheduled a time for you to meet your medical team and ask them any questions you have, as well as for them to walk you through the treatment you will be undergoing. 

Services Included In Your Treatment

  • Medical general assessment. 
  • Critical care evaluation. 
  • Specialist doctor evaluation. 
  • Anesthesiology evaluation. 
  • Perioperative care. 
  • Pharmacy and Supplies. 
  • Operating room.
  • Anesthesia Services. 
  • Diagnostic/therapeutic imaging. 
  • Autologous stem cell acquisition. 
  • Pathology services. 
  • Hemodynamics suite.
  • Patient coordination fee.
  • Catheterization procedure.
  •  Mannitol injection.
  • Med Surg Supplies sterile.
  • Spinal tap procedure.
  • Recovery.
  • Laboratory fee.
  • Culture/Expansion autologous BM derived stem cells.
  • Med Surg room.
  • IV infusion.
  • Follow up and recommendations.
  • Pick up / Drop off from airport to accommodation and vice versa.
  • Pick up/Drop Off the day of the procedure to and from hospital.
Understanding what causes your medical condition

The cause of multiple sclerosis is unknown. It’s considered an autoimmune disease in which the body’s immune system attacks its own tissues. In the case of MS, this immune system malfunction destroys the fatty substance that coats and protects nerve fibers in the brain and spinal cord (myelin).

Myelin can be compared to the insulation coating on electrical wires. When the protective myelin is damaged and nerve fiber is exposed, the messages that travel along that nerve may be slowed or blocked. The nerve may also become damaged itself.

It isn’t clear why MS develops in some people and not others. A combination of genetics and environmental factors appears to be responsible.

Risk factors
These factors may increase your risk of developing multiple sclerosis:

Age. MS can occur at any age, but usually affects people somewhere between the ages of 16 and 55.

Sex. Women are more than two to three times as likely as men are to have relapsing-remitting MS.

Family history. If one of your parents or siblings has had MS, you are at higher risk of developing the disease.

Certain infections. A variety of viruses have been linked to MS, including Epstein-Barr, the virus that causes infectious mononucleosis.

Race. White people, particularly those of Northern European descent, are at highest risk of developing MS. People of Asian, African or Native American descent have the lowest risk.

Climate. MS is far more common in countries with temperate climates, including Canada, the northern United States, New Zealand, southeastern Australia and Europe.

Vitamin D. Having low levels of vitamin D and low exposure to sunlight is associated with a greater risk of MS.

Certain autoimmune diseases. You have a slightly higher risk of developing MS if you have thyroid disease, type 1 diabetes or inflammatory bowel disease.

Smoking. Smokers who experience an initial event of symptoms that may signal MS are more likely than nonsmokers to develop a second event that confirms relapsing-remitting MS.

Complications
People with multiple sclerosis may also develop:

  • Muscle stiffness or spasms
  • Paralysis, typically in the legs
  • Problems with bladder, bowel or sexual function
  • Mental changes, such as forgetfulness or mood swings
  • Depression
  • Epilepsy

Most people with MS have a relapsing-remitting disease course. They experience periods of new symptoms or relapses that develop over days or weeks and usually improve partially or completely. These relapses are followed by quiet periods of disease remission that can last months or even years.

Small increases in body temperature can temporarily worsen signs and symptoms of MS, but these aren’t considered disease relapses.

About 60 to 70 percent of people with relapsing-remitting MS eventually develop a steady progression of symptoms, with or without periods of remission, known as secondary-progressive MS.

The worsening of symptoms usually includes problems with mobility and gait. The rate of disease progression varies greatly among people with secondary-progressive MS.

Some people with MS experience a gradual onset and steady progression of signs and symptoms without any relapses. This is known as primary-progressive MS.

CONTACT US

Cellular Hope Institute – Datran Center 9100 S Dadeland Boulevard, Suite 1500. Miami Fl. 33156 United States

305 560 5337

info@cellularhopeinstitute.com

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